MRPL12 antibody

Catalog No. ABIN7074638

This Rabbit Polyclonal antibody specifically detects MRPL12 in WB, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MRPL12 antibody (ABIN7074638)

Target: MRPL12 (Mitochondrial Ribosomal Protein L12 (MRPL12))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL12 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MRPL12 Antibody

Cross-Reactivity: Mouse, Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Human MRPL12

Application Details

Application Notes: WB (M,R) 1: 500-1: 1000, IHC/IF (H) 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for MRPL12

Target: MRPL12 (Mitochondrial Ribosomal Protein L12 (MRPL12))

Alternative Name: MRPL12

Background: MRPL12 is a component of the 39S subunit of mammalian mitochondrial ribosomes, and is encoded by a nuclear gene. The protein forms a homodimer, localizes predominantly to mitochondria and binds to the large mitochondrial ribosomal subunit. It is required for CycD/Cdk4- induced cell growth. In addition, forming a ribosomal stalk with MRPL7, MRPL12 is required for the recruitment of translation elongation factors Tu and G to the large ribosomal subunit . It also a part of a novel regulatory mechanism that coordinates mitochondrial transcription with translation and/or ribosome biogenesis during human mitochondrial gene expression.

Molecular Weight: 21 kDa

Gene ID: 56282

NCBI Accession: NP_081480

UniProt: Q9DB15